Two New Toronto area residents are waking up in hospital in serious condition after a motorcycle and a Toronto Police cruiser collided near Sixth and Birmingham Streets.

The police watchdog, the Special Investigations Unit, is investigating the collision that took place in the area of Sixth and Birmingham Streets, just north of Lake Shore Blvd. W., around 8 p.m. on May 13.

Toronto paramedics say a woman in her 30s and another person were transported to trauma centre with serious but non-life-threatening injuries.

No one was injured in the police vehicle.

A video posted on social media shows the police vehicle travelling on Sixth, which is a one-way street.

Residents allege the vehicle was travelling the wrong way in a one-way street when the crash occurred.

Police officials said they cannot comment on the case due to the SIU investigation underway.

Some streets in the area were closed as police investigated the incident.

No charges have been laid at this time.

Police did not say if the officers were on their way to a call at the time the accident occurred.

The names of the injured residents have not been released.